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Nediljko Budiša - Znanstveni interesi

Pregled istraživačkih interesa za znanstvenika:

Interesi: Experimentalna evolucija genetickog koda

Vise detalja (na engleskom jeziku):

Nediljko Budisa research at the interface of chemistry and biology is mainly concerned with the possibilities to generate novel generic classes of amino acids by using synthetic chemistry, bio-computing and target-engineered metabolic circuits. Such novel amino acids should enable an expansion of the genetic code in the context of a reprogrammed protein translation. The final goal is to create designer molecules and cells carrying out novel properties optimized for user-defined environments or to engineer a genetic code such that proteome-wide substitutions/insertions of synthetic amino acids can yield a synthetic life with new chemical possibilities.